How Cholesterol Helps Cancer Spread


You may have heard the latest cholesterol fear story from conventional medicine. They're now saying that it can make cancer grow faster. But is it true?

Researchers have been trying to connect cholesterol to breast cancer for some time. Now they're saying it can push any cancer to grow faster. In this new study, they're saying that the metabolism of cholesterol in the body produces a molecule called 27HC. And 27HC is very dangerous. That's because it tells your immune cells to ignore cancer.

Normally, the immune system is able to target and destroy cancer cells. But 27HC tricks your immune system into thinking cancer is fine. The researchers found that if they inhibited the enzyme that makes 27HC in mice, breast cancer metastasis was suppressed. But if they fed the mice a high-cholesterol diet and just let the systems run their course, breast cancer grew rapidly.

The researchers surmised that because 27HC essentially hijacks the immune system, it might be a culprit in other forms of cancer too. Sure enough, they found that 27HC was involved in increased metastasis in colon cancer, lung cancer, melanoma, and pancreatic cancer.

The researchers are now turning their attention to humans to confirm the pathway works the same way in us. If it does, they're of course hoping to develop drugs that target 27HC to interrupt the metastasis process. But this is where we have to begin to ask questions about the research.

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Some of my oldest female patients, including my 91-year-old Mama, have high cholesterol. I think there are other parameters that have not yet been revealed by this research that impact the production of 27HC and its circulation in the female body. For instance, do HDL, trigylcerides, and sugar have an impact?

If a woman has healthy HDL, triglycerides, and sugar levels, are they as susceptible to the negative impact of 27HC? We know that when there's more fat eaten than the body can digest, it creates a cascade of negative metabolites. So, is it cholesterol that's the problem? Or is the real problem improperly digested fat? Obviously, I suspect the latter. Unfortunately, this study doesn't tell us the quality of fat these mice were eating. Since it was "high cholesterol," it's likely the quality was low and the amount was high.

It's most helpful, especially in light of this research, to begin a healthful lifestyle and not eat excessive amounts of anything. The key to remaining healthy is moderation. It's also possible there are natural things we can do that interrupt the metastasis process.

For instance, if you have high or high-normal cholesterol, or if your triglycerides tend to be high or high-normal please consider Mediterranean Cholesterol Formula. It's full of nutrients rich in phytochemicals that will help your body handle cholesterol in a healthy way. I have had so many patients and readers report not only that their cholesterol levels returned to more healthy levels, but their HDLs have risen, and their VLDLs and triglycerides lowered. This formula not only addresses your cholesterol, but the various moving parts of your cardiovascular and metabolic systems. If you do try Mediterranean Cholesterol Formula, please let us know how it works for you.

Better Health and Living for Women,

 







Amy E. Baek, Yen-Rei A. Yu, Sisi He, Suzanne E. Wardell, Ching-Yi Chang, Sanghoon Kwon, Ruchita V. Pillai, Hannah B. McDowell, J. Will Thompson, Laura G. Dubois, Patrick M. Sullivan, Jongsook K. Kemper, Michael D. Gunn, Donald P. McDonnell, Erik R. Nelson. The cholesterol metabolite 27 hydroxycholesterol facilitates breast cancer metastasis through its actions on immune cells. Nature Communications, 2017; 8 (1) DOI: 10.1038/s41467-017-00910-z

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