Metformin Works With Gut Bacteria to Fight Diabetes

Volume 14    |   Issue 25

Did you know that researchers don't know why one of the most popular drugs for diabetes works? It's true. All they know is that it does indeed work.

This treatment that's eluded researchers' explanation for years is the medication metformin. Doctors use it to help people with type-2 diabetes control their blood sugar. It's been a treatment of choice for more than 60 years. But, believe it or not, no one really understood how or why it works. Until recently, that is. Researchers at Sahlgrenska Academy in Sweden and the University of Girona in Spain have finally cracked it.

You probably know by now that the bacteria that form the microbiomes in our guts affect nearly every aspect of our health. Type-2 diabetes is no different. And it seems that metformin affects the balance of these bacteria, helping to improve metabolism.

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For this study, the researchers transplanted gut microbiota from 22 patients before and after they received metformin to bacteria-free mice so they could study the effects of the medication. Their findings help explain why some people really benefit from metformin, while it doesn't make a difference for others — individual variations in microbiomes are likely to blame. This also helps explain why some people suffer from diarrhea and abdominal pain when taking metformin.

These findings suggest that a good probiotic, such as Advanced Probiotic Formula, could help people with type-2 diabetes manage the disease. A large percentage of individuals with high blood sugar or diabetes present with gastrointestinal symptoms — and probiotics can help. It's a great place to start, as feeding the healthy bacteria in your gut will have a ripple effect of health benefits throughout your body.

However, if you've taken a probiotic for a while and are still experiencing these symptoms, you may need something to go along with the probiotic. In that case, I recommend you consider a course of activated charcoal, which can help with leaky gut symptoms associated with excess sugar. Oftentimes, charcoal taken away from the probiotic by at least an hour will help to absorb gas often created from excess sugar.

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