Researchers have identified an estrogen receptor called GPER that’s found throughout the cardiovascular system. Because it’s so abundant, they concluded that estrogen plays a significant role in cardiovascular functioning and coronary artery disease. But to enjoy these benefits, you have to use the right type of estrogen.
What most reports don't tell you is that there are a number of variables involved in hormone safety. For instance, are you using synthetic hormones or bioidentical hormones? Is the doctor administering them knowledgeable and skilled at personalizing dosage or does he or she try to use a one-size-fits-all approach? The answers to these questions can have an enormous impact on the outcome of hormone use.
In the 1990s, several studies found that using hormones could have negative effects on cardiovascular health in women. But these studies were conducted with hormones derived from horses (conjugated equine estrogens) and synthetic progestins. In the decades since, we've learned quite a bit about how hormones affect women and how to utilize them in a healthier, safer, more beneficial manner.
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A study recently published in the journal Advances in Pharmacology re-addressed hormones and women's cardiovascular health. Researchers have been investigating how estrogen signaling works, and they've identified an estrogen receptor called GPER that's found throughout the cardiovascular system. Because it's so abundant, researchers have concluded that estrogen plays a significant role in cardiovascular functioning and coronary artery disease.
The research is ongoing, but so far, scientists have discovered that activating GPER can help protect women from coronary artery disease. You just need to do it with the estrogen your body is used to. That would be bioidentical estrogen — not estrogen from a horse's urine. This helps provide evidence that estrogen replacement can be beneficial for postmenopausal women who are concerned about their heart health.
Of course, the researchers want to continue pursuing this topic in hopes of developing a cardiovascular drug. But hormone replacement can be beneficial. Just make sure you find a reputable doctor who works to tailor your plan to your specific issues. And be sure you're using bioidentical hormones, not ones that come from a source proven to be dangerous to your cardiovascular system, such as horses. There are plant options containing phytoesterols, which you can experiment with and see how you feel. These include black cohosh, red clover, chaste-tree berry, dong quai, evening primrose, ginkgo, and even ginseng. You would want to try one of these at a time in a low dose and rotate. If you have a condition, such as a history of genetic breast cancer, you may want to try Maca. Femessence is a product that, in fact, does not claim to have phytoestrogens, but impacts your own hormones in a positive way. If you try Femessence, it's best if you take it by itself. Generally, Maca should not be combined with other herbs or hormones if your goal is to help balance your hormones.